2 years after the events of "Universal Monsters: The Mummy Legacy", the O'Connell family has found a reason to live since they met certain "monsters" who helped them during their last adventure, these even living in their mansion with them. However, Count Dracula and his new allies have a new plant to make this world a world for Gods and Monsters, finding the old place where the Oasis of Am-Shere was, where he managed to bring back the King Scorpion to life ! Together, they have a dark project : to use the blood of the worst enemy of his family, the last Van Helsing, to summon a powerful demon in this world. However, Doctor Jack Griffin, aka the Invisible Man, becomes aware of all this and goes to inform the O'Connells of what is going on. These and their friends are therefore preparing for a new adventure, while Gabriel Van Helsing also goes in search of them, after the terrible Headless Horseman, controlled by Baba Yaga, one of Dracula's accomplices, has been sent to his trace. Finally, one of the Count's accomplices, Doctor Praetorius, a great admirer of Frankenstein's work, years ago created a "Fiancée" for Victor's "monster", with the aim of using it to get him to join him, but he seems to have worked way too much with Lilith. If the O'Connells thought they had done the hardest part with Dracula the last time, they will discover that they are still far from it...
