It's now been 4 years since Megamind and Tighten fought, and MM and Minion are now the heroes of Metro City... But they're still not trusted enough. But when a new hero calling himself Mendax enters Metro City and when the mayor is found as a dehydrated cube, the city believes he's back to his old tricks. With the help of Roxanne Ritchi, Minion and a tired Metro Man, Megamind will need to prove his innocence.
