Medusa is a normal human, who, like many of us, is overwhelmed with trying to fit a certain mold to please others. Her resulting popularity ticks off the wrong Goddess who turns her into the snake-haired monster we all know and fear. Medusa sets out on a quest to reverse this curse with the help of a goofy team of oddball and misfit mythological creatures who help her learn that what makes you different is, in fact, what makes you strong.