Following the death of Jean DeWolff, Peter Parker takes her adoptive Ana Kravinoff into his care and moves house, paid for by Silvija Sablinova. However, Peter’s life is turned upside down by the return of the man who ruined his life, Mysterio.
Meanwhile, gang violence has escalated on the streets, one individual being implicated in them. When vigilante Daredevil contacts Spider-Man for assistance, they together uncover a criminal conspiracy that traces back to Wilson Fisk. And the key to it all may be an old foe in Sasha Kravinoff, who wants to meet her long-lost daughter…