After the events of Spider-Man: No Way Home, Peter Parker attempts to balance new friendships, old relationships, a new job, his volunteer work at F.E.A.S.T., an internship with his brilliant yet distant professor, and his studies at Empire State University on top of his responsibilities as the friendly neighborhood Spider-Man. But when a mysterious new threat rears its head through brutal murders of police officers and his alter-ego is blamed, Peter must question whether or not he should continue on as the Amazing Spider-Man.