Following the battle against Norman Osborn, the corrupt businessman has now suffered selective amnesia and has seemingly forgotten the identity of both himself and Spider-Man. With this, Peter Parker now has it better than ever with barely any issues at all. He's managed to keep himself in a committed relationship with his dream girl Gwen Stacy, and he's managed to keep his double life a secret for the most part. Even though the new villains he's facing are tough, he's prepared. But what he's not prepared for will change his life...possibly forever.