Spider-Man follows Peter Parker (Tom Holland), an orphaned high schooler who pines after popular girl-next-door Mary Jane Watson (Meg Donnelly). While on a science class field trip, Peter is bitten by a genetically-engineered "super spider." As a result, Peter gains superhuman abilities, including increased strength, speed, and the abilities to scale walls and generate organic webbing. After his beloved Uncle Ben (Tobey Maguire) is murdered, the teenager realizes that he must use his newfound abilities to protect New York City. Meanwhile, wealthy industrialist Norman Osborn (Matthew McConaughey), the father of Peter's best friend Harry Osborn (Timothee Chalamet), subjects himself to an experimental performance-enhancing serum, which creates a psychotic and murderous split personality. Donning a military battlesuit, Norman becomes a freakish "Green Goblin", who begins to terrorize the city. Peter, as Spider-Man, now must do battle with the Goblin, all while trying to express his true feelings for Mary Jane.
