Despite his success alongside the Avengers, Hank can't shake the guilt he carries, the deaths of Vernon and Dare. He and Jan are in a relationship now, but the guilt he carries gets in the way, no matter how much Jan tries to help him. He feels small; his power to shrink to the size of an ant doesn't help much.
Hank has been locking himself in his lab for the past few days, which distances him from Jan, who puts an end to it, deciding it's time for a date/adventure. As Ant-Man and the Wasp, the two help with rescues, fires, accidents, and saving lives, which makes Hank feel better about himself. That's why he wanted to be Ant-Man from the beginning, to help people.
However, the two are transported to an alien planet outside the solar system, where the planet is about to collapse and they need the help of those who call themselves Earth's greatest heroes. The local princess, who assigned the heroes' help, shows interest in Hank, much to Jan's jealousy and amusement, as Hank didn't know how to handle the attention.
As Ant-Man and the Wasp, the duo go to the planet's core, discovering the reason for the threat and preventing the collapse of that world. They are celebrated as the heroes they are.