While working in the Florida Everglades, Dr. Theodore Sallis is supposedly killed after injecting a new version of the super soldier serum into his arm and being driven off the road and crashing into a swamp. He then becomes the strange being: Man-Thing. He has to figure out what he is before a terrorist organization figures out what really happened. At the same time, Sallis' wife tries to figure out what happened to her late husband.
