Nitrus Brio, better known as N. Brio, is an mad scientist and a recurring antagonist in the Crash Bandicoot series. He is commonly credited as the inventor of the Evolvo-Ray, a device that turns ordinary animals into soldiers for Neo Cortex.[1] N. Brio made his first appearance in the original Crash Bandicoot game as Cortex's right-hand man, but his allegiance has varied throughout the series since, working with Crash in Crash Bandicoot 2: Cortex Strikes Back, working for N. Tropy in Crash Twinsanity, and even working with Cortex again in Crash Bash, Crash: Mind Over Mutant, and Crash Bandicoot 4: It's About Time. N. Brio commonly uses potions both as weapons and to transform himself.