The supreme intergalactic being "Brainiac" has arrived on Earth to annihilate every last human being and begin a new population. As a result of these events, Batman, Superman, Wonder Woman, Aquaman, the Flash, and Green Lantern are united by the telepathic alien "Martian Manhunter", the Humanoid robotic man "Cyborg" and former member of the Thanagarian military "Hawkgirl" to create the Justice League of America, aiming to confront this significant threat.