In a world decimated by "Captain Trips," a super-flu that kills 99% of the population, the few survivors are haunted by prophetic dreams. They are called west by Mother Abagail, a 108-year-old woman who represents the remaining light, and east by Randall Flagg, a grinning, darkly charismatic figure who embodies pure, chaotic evil.
As the survivors—including Texas everyman Stu Redman, pregnant young Frannie Goldsmith, struggling musician Larry Underwood, deaf-mute drifter Nick Andros, and gentle giant Tom Cullen—journey across a corpse-choked America, they must choose a side. The film follows their harrowing paths through plague, tornadoes, and madness, culminating in their gathering in Nebraska. As Flagg amasses his followers in Las Vegas, the stage is set for a final confrontation between good and evil, ending on a cliffhanger as the dark man's red eye opens and Trashcan Man whispers, "My life for you."