Three years after his wife and baby daughter were murdered by junkies high on an unknown designer drug, undercover DEA agent Max Payne is framed for the execution of his own partner. Hunted by the NYPD and the mob, Max carves a bloody path through New York's criminal underworld, uncovering a conspiracy that reaches from a sleazy Bronx hotel to the glass tower of Aesir Corporation, whose CEO authorized the murders as a field test for a failed military drug called Valkyr. Betrayed by another partner he trusted, aided only by a contract killer avenging her twin sister and a Russian gangster with a code, Max must survive a city buried in snow and corruption long enough to put a bullet in the woman who took everything from him.