female
First appeared in Incredible Hulk Annual #6 in 1977 and was created by Len Wein, David Kraft, and Herb Trimpe. Her was created as Paragon with the help of Doctor Strange by a group of scientists called the Enclave, who also created Adam Warlock/Him.
Ayesha (Marvel)
Confirmed Villains
for Confirmed Villains in Heroes and Villains in/for the MCU
Suggested by kpylesroxx
You get the idea…