Dr. Venkman, Dr. Stantz, and Dr. Spengler lose their university jobs in New York following their first face-to-face encounter with the supernatural. The group’s mouth and wit, Dr. Venkman suggests they pursue new careers as ghost-hunters, and it isn’t too long before they end up being visited by Dana Barrett, a young woman who claims to have accidently opened the gates to hell in her own appartment.