Years after killing her vampire neighbor, Jerry Dandrige, after therapy, Charley Brewsterse convinces herself that it was all a fantasy from her imagination. One night when he goes to see his friend, the actor Peter Vincent, a sensual woman with a very diverse group, called Regine, moves into the same building. After a series of strange and confusing events, it is discovered that this woman is none other than the sister of the vampire that she killed years ago.