Set in suburban Columbus, Ohio, during the Reagan administration, Steven and Elyse Keaton are baby boomers, liberals and former hippies, raising their three children: ambitious, would-be millionaire entrepreneur Alex; fashion-conscious, gossipy Mallory; and tomboy Jennifer. Married in 1964, Elyse is an independent architect and Steven, a native of Buffalo, New York, is the station manager of WKS, a local public television station.