The series follows the dysfunctional Griffin family—father Peter, mother Lois, daughter Meg, son Chris, son Stewie, their anthropomorphic dog Brian, and adoptive sons John and Tyler, all of whom reside in their hometown of Quahog. The show features the voices of John Goodman, Elizabeth Perkins, Jonah Hill, Mila Kunis, Ashton Kutcher, Ryan Phillippe, series creator Seth MacFarlane, and Jason Alexander in the roles of the Griffin family.
