Walt Disney's famous cartoon star, Mickey Mouse and his band of friends run a night club called the "House of Mouse" in the middle of Main Street in the city of Disneyville, which shows Disney cartoons as part of its floor show. Each episode features a framing plot revolving around the comic mishaps of Mickey and the other characters running the club, often with cartoons that fit the theme of the framing plot, which are used as wraparounds for various Disney cartoons.