The drama follows a group of highly trained profilers in the fictional National Criminal Investigation (NCI) team who track down criminals to solve cases. It begins a year after a crucial error results in a bomb detonating at a hospital, killing several SWAT officers and leaving the NCI team leader Ryunosuke Shimazaki's confidence badly shaken. He returns to work after a long break and is immediately drawn into a serial murder case which requires the NCI team to collaborate with the local police agency's Violent Crimes Unit. They meet the temperamental police officer Eiji Tachibana, who appears to have a bitter grudge against Ryunosuke Shimazaki.