Ezekiel "Zeke" Sims is a fictional character appearing in American comic books published by Marvel Comics, usually as a supporting character in stories featuring Spider-Man and Silk; versions of the character from alternate timelines are also featured in the 2014 crossover event Spider-Verse. Characters based on Ezekiel appear in the films Spider-Man: Across the Spider-Verse (2023), voiced by Mike Rianda, and the live-action Sony's Spider-Man Universe (SSU) film Madame Web (2024), portrayed by Tahar Rahim. Ezekiel Sims was a rich businessman who, in his younger years, ritualistically gained powers similar to those of Spider-Man. He aspired to use his powers to be a hero, but instead used them to create and develop a corporation, realizing that he could not do anything without a base of operations. He swiftly became too busy to use his powers on a daily basis. When Spider-Man emerged, Ezekiel hired six independent and private detectives to investigate Spider-Man's life, allowing him to piece together who Spider-Man was from the various pieces of information they provided him. Ezekiel, in his 50s, contacted Spider-Man explaining to him the nature of animal totems: people who gain supernatural abilities from a mystic link to certain animals. He suggested that the spider that bit Peter Parker was not mutated by the radiation, but actually trying to give Peter its powers before the radiation killed it. This meant that Spider-Man was now part of the supernatural food chain, and became a target for other totems and beings who feed on totems (Thus why many of Spider-Man's foes were based on animals to some level; they 'sensed' Peter to be a true totem, thus motivated to destroy him as they were merely impostors]). He subsequently aided Spider-Man in fighting a being known as Morlun, a vampire-like entity that 'fed' on totems, apparently at the cost of his life. It was later revealed that he survived and departed for Africa, where he aided Spider-Man in dealing with Shathra, another supernatural-based menace, by leading Peter to an area where he would have the advantage over Shathra. It was noted that the vast supernatural menaces that Spider-Man had to face were really after Ezekiel. In an attempt to direct the consequences of gaining his powers onto Spider-Man himself, Ezekiel took Spider-Man to the temple where he had been given his powers and drew blood to attract a massive spider that would take the 'false' totem warrior as a sacrifice. However, in his last moments, he realized that he had done nothing with his powers but help himself, while Peter had selflessly risked his life to save others repeatedly. For this, he attacked the spider that would have eaten Peter, giving his own life to save his friend in recognition of the hero that Peter truly was, thus gaining a chance at redemption. In Grim Hunt, a reanimated Ezekiel (covered in spiders) appeared before Spider-Man and Arachne. Unknown to Spider-Man, the Ezekiel that appeared before him was really the Chameleon in disguise leading Spider-Man into a trap with the Kravinoffs in order to carry out the resurrection of Sergei Kravinoff, which required the blood of Spider-Man. During the "Original Sin" storyline following the murder of Uatu the Watcher, Spider-Man's exposure to Uatu's eye during the confrontation with the Orb revealed that Cindy Moon, the second person bitten by the radioactive spider that created Spider-Man, had been held in isolation by Ezekiel. He educated her on how to use her powers but kept her locked in a secret room underneath his office after speaking with Cindy's parents Albert Moon Sr. and Nari Moon. He also appeared to her and Spider-Man in the form of a prerecorded message telling Silk that if she leaves the lair, there is no hope for them all (likely referring to the Spider-Totems). It is also revealed that Ezekiel had kept Silk safe in her lair to prevent Morlun from finding out. Years later, Spider-Man learns about Silk and frees her from Ezekiel's bunker, allowing her to start a new life and career. This ends up triggering the multiversal hunt of all spiders as the Inheritors are now aware of Silk's existence as the "Bride". Ezekiel's organization is later taken over by Tamara Phearson under his alias of Fang.