Somewhere southeast of Australia rest three little islands, teeming with wildlife. On one of these islands resides Doctor Neo Cortex, who along with his assistant N. Brio are trying to create an animal army known as the "Cortex Commandos" to achieve world domination. Crash Bandicoot, a peaceful bandicoot, who is slated to become the army's general. Dr. N. Brio has created a machine known as the Evolvo-Ray, which is capable of giving animals anthropomorphic traits. Dr. Cortex eventually subjects these creatures to the Cortex Vortex, a device designed to brainwash animals and make them obedient to him. Despite Dr. Brio's warning that the Vortex was unstable, Cortex rushed the newly evolved Crash into the Vortex, which rejects him.