John Constantine is a jaded, chain-smoking, working-class English magician and con artist who has dedicated his life to tracking down demons and other malevolent entities. He frequently finds himself caught up in supernatural plots and personal ruin while attempting to rescue himself or others, relying on his streetwise instincts and cleverness as much as his mystical expertise. One day, as he investigates a series of murders to which Mary “Zed” Martin is framed for, Constantine travels from London to Africa and then the US to combat a hunger spirit that has been unleashed on New York City. At this moment, Constantine is required to take every necessary action to rescue the human realm from total and absolute darkness.