Set in the 1960s during the Cold War, the game's campaign follows CIA operative Alex Mason as he attempts to recall certain memories of combat to locate a numbers station. This station is due to transmit broadcasts to sleeper agents instructing them to deploy chemical weapons across the United States.
in the late 1980s and 2025. In the 1980s, the player switches control between Alex Mason and Frank Woods, two of the protagonists from Black Ops, while in 2025, the player assumes control of Mason's son, David (codenamed "Section").
