Walter White, a brilliant but struggling chemistry teacher diagnosed with cancer, turns to manufacturing methamphetamine with his former student Jesse Pinkman in order to secure his family's financial future. Their partnership quickly draws them into a dangerous criminal world filled with violence, betrayal, and powerful drug dealers.
As Walter becomes increasingly ruthless and ambitious, Jesse struggles to survive the consequences of their criminal operation. Their lives become entangled with the violent Tuco Salamanca, while Walter's transformation into the ruthless Heisenberg threatens everything he once cared about.