Big Nate follows the adventures and misadventures of Nate Wright, a rebellious yet spirited male sixth-grader, along with his fellow classmates and teachers. He is portrayed as a boy with very little interest in studies or conforming to standards, which has led him into several conflicts with his social studies teacher Mrs. Godfrey, whom he considers to be his nemesis. Strips also focus on Nate's home life and friendships with his best friends Francis and Teddy. Answering questions from fans in the Washington Post, Peirce revealed the following about the creation of the strip.
