San Francisco, January 1999, two years after Lola's birth in May. Charlie and Itchy are with David, Sasha is running the Fleabite Café, Carface, Killer and Max are reformed, David's stepmother Claire has taken off the baby weight due to Lola's birth, and Red and Annabelle's evil cousin Belladonna are long gone. But nothing goes well when Sasha does a road trip to Albuquerque.