Ramonda was the Queen of Wakanda, wife of T'Chaka, and mother of T'Challa and Shuri. She stood by her son's side when he became King of Wakanda, but was soon forced into exile when Erik Killmonger defeated T'Challa in ritual combat and took over the throne. Ramonda fled with Shuri, Nakia and Everett Ross to Jabari Land. There, she was reunited with her son T'Challa, who she saved thanks to the powers of the Heart-Shaped Herb. Ramonda remained in Jabari Land while T'Challa and his allies left to fight Killmonger, only to return in the Golden City following T'Challa's victory. After the Battle of Wakanda, she became queen regnant of Wakanda after both T'Challa and Shuri were killed in the Snap. Although they were resurrected after the Blip, Ramonda would assume the position of queen once again after T'Challa passed away of an unexpected disease. With geopolitical relationships growing strenuous over Wakanda's private reserves of Vibranium, Ramonda was confronted by Namor, who threatened war against Wakanda unless they could locate the scientist responsible for creating the underwater vibranium detector that threatened their livelihood. When Nakia rescued Shuri and Riri Williams from Talokan, it ignited the Talokanil-Wakandan War, where Ramonda was killed during Namor's attack.