Mister Hyde (Calvin Zabo) is a supervillain appearing in American comic books published by Marvel Comics. Created by writer Stan Lee and artist Don Heck, the character first appeared in Journey into Mystery #99 (December 1963). Calvin Zabo is a supervillain known under the codename of Mister Hyde and has been a known collaborator of Cobra.[3] He is the father of the superhero Daisy Johnson.[4] The character has also been a member of the Masters of Evil.[5] Calvin Zabo appeared in the second season of the television series Agents of S.H.I.E.L.D., portrayed by Kyle MacLachlan.